The study found that gamma cyclodextrin can increase the bioavailability of curcumin by 40 times.

As a bioactive component contained in the rhizome of turmeric, Curcumin is not only a potent antioxidant, but also has anti-inflammatory, antibacterial and anti-allergic functions. However, curcumin is not water-soluble, so it is difficult to be absorbed by the human blood circulation system, but its bioavailability can be significantly improved by means of gamma cyclodextrin. This effect is now scientifically proven again.

In an independent clinical cross-blinded study in the United States, CAVACURMIN® (gamma cyclodextrin-curcumin formulation) containing pure Curcumin Extract (95% purity) and two commercially available products The curcumin preparations used to improve bioavailability were compared and blood tests were performed on testers who took the corresponding curcumin every 12 hours. Test results show that the body's absorption of CAVACURMIN® is about 40 times higher than traditional curcumin extract, and at least 4.6 times higher than the market-selling products that win in the experiment.

This cyclic oligosaccharide gamma cyclodextrin enhances the bioavailability of curcumin with its unique properties: gamma cyclodextrin has a hydrophilic shell and a hydrophobic cavity, and the molecular cavity can accommodate other ruthenium Aqueous substances, therefore, cyclodextrin can bind different substances together, release active substances, and stabilize sensitive substances or interfaces.

For example, inclusion of fat-soluble curcumin in the interior of water-soluble gamma cyclodextrin can increase its bioavailability. At this time, the hydrophobic curcumin obtains a hydrophilic outer shell that forms a molecular emulsion that is more easily absorbed by the body.

As a dispersible powder with fluidity, CAVACURMIN® can be used as a dry or powdered nutritional supplement for tablets, capsules, energy biscuit bars, and also for functional beverages. Not only does cholesterol have no cholesterol, it does not contain allergenic ingredients, but it also provides a purely botanical alternative to many nutritional supplement formulations. WACKER uses fully renewable raw materials – through the enzymatic hydrolysis process – to produce cyclodextrin.

Dr. Helmut Reuscher, Director of Food Sales and Technology, Wacker Biotech Business Unit, said, “We are very pleased to see clinical research confirming the efficacy of gamma cyclodextrin in improving the bioavailability of curcumin. Our customers are increasingly focusing on nutrition. High bioavailability of supplements. We are proud to see WACKER's innovative cyclodextrin technology being used in a wider range of applications, and WACKER customers can use it to better develop and improve nutritional supplements."